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GLP-1 Receptor Activation: Semaglutide binds to and activates GLP-1 receptors, which are expressed in various tissues including pancreatic islets, the gastrointestinal tract, and the central nervous system

Implications for Chronic Kidney Disease and Global Health Lead author Professor Sunil Badve, Professorial Fellow at The George Institute for Global Health and UNSW Sydney said the study expanded current knowledge about this class of drugs in key areas, including benefits in people with CKD, and in people with and without diabetes

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Their scale means generally reliable stock levels and consistent formulation quality

Thoughtful perspective from David Blair, and strong reporting from The Wall Street Journal

Additional file 2: Fig