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The delayed gastric emptying induced by semaglutide means the stomach retains food for longer periods, which may create the subjective experience of the stomach being "smaller" because patients feel full after consuming less food
doi: 10.1016/j.euroneuro.2023.12.010 2 OwenMJSawaAMortensenPB
Shown in a blinded split-face study published in the Journal of Drugs and Dermatology to deliver statistically equivalent results to the gold standard (4% hydroquinone) physician assessment with superior average improvement in the appearance of discoloration, fine lines and wrinkles leading to significantly higher consumer preference
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Statistical analysis of the primary endpoint was performed using a linear normal model for censored data with log-transformed AUC 024h,sema,Day10 as a dependent variable, dosing schedule group (five levels) and sex as fixed effects, and a residual variance parameter for each dosing group
