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So far, clinical trials have not shown any specific impact on sleep

and anotia (the external portion of the ear is missing)

However, many patients were unable to tolerate the full dose due to side effects and maintained using lower dose of 1.2, 1.8 or 2.4 mg/day

Analysis of tirzepatide acquisition costs and weight reduction outcomes in the United Kingdom: insights from the SURMOUNT-1 study

If a weekly dose was missed, protocols allowed a late injection within a certain window or skipping to the next scheduled administration

Now, statistically underpowered studies happen, especially where research resources are limited and that doesnt mean that the results arent worth considering