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Downstream to chemical damage, unrepaired biological structures can trigger cascading cellular events which may ultimately determine cell malfunctioning and death or unrestricted replication leading to cancer [15]

Proponents argue this preserves more of the body's natural feedback regulation, since the pituitary can still respond to its normal control signals

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This JAMA piece notes that Bridge prescriptions may come from clinicians who are not enrolled in Medicare

Wegovy is also FDA-approved to treat metabolic dysfunction-associated steatohepatitis (MASH), a condition that causes inflammation and scarring in the liver, including more serious scarring called advanced fibrosis