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However, the reduction of GSH and GCL mRNA levels was more pronounced in most tissues from the male mice, compared to those from the female mice

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Biochim Biophys Acta Mol Basis Dis 1689(1):612 Ichikawa H et al (2007) Anticancer drugs designed by mother nature: ancient drugs but modern targets

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Originally characterized at the University of Florida by the Stephen ORahilly and Robert Kraft groups, the compound has been studied in preclinical research for body composition, adipose tissue lipolysis, glucose homeostasis, skeletal muscle aging, and metabolic disease endpoints