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RNA - seq indicates that DHA/EPA may enhance the efficacy of bortezomib by activating ferroptosis - related signaling pathways, suggesting that ferroptosis may play a positive role in improving drug sensitivity and overcoming drug resistance in the treatment of MM ( In conclusion, ferroptosis - related genes may become important factors for MM prognosis assessment, and more relevant genes still need to be explored through experiments

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However, due to the drugs immune suppressing effects, those taking Tocilizumab are at an increased risk for serious health conditions, including infections that may lead to hospitalization or death (MD Consult 2012)