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Core Comparison: Small molecules lead in convenience and cost efficiency, but face drawbacks including harsher gastrointestinal side effects, unvalidated long-term safety profiles, and limited multi-target development potential

doi: 10.1016/j.cotox.2018.01.002

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In a murine myocardial infarction model, miR-92a inhibition improved endothelial cell function and postinfarction recovery by modulating autophagy-related genes in an endothelium-specific manner