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Current neuropharmacology , 13 (1), 7188

Newly synthesized proteins targeted to lysosomes can be transported either directly into the lysosome through the trans-Golgi network depending on receptors, including mannose-6-phosphate receptor, sortilin, and lysosomal integral membrane protein type 2 87,88 , or indirectly ingested into the lumen by endocytosis 89

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And the sublingual formulations that compounding pharmacies produce have absorption characteristics that change everything about when and how often you should dose

No severe adverse events were reported