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This was later summarized by The Wall Street Journal

The accumulation of lipids and their metabolic byproducts within and between muscle cells can lead to mitochondrial dysfunction and subsequent declines in muscle strength and function

Once someone has been on the same dose for several weeks, gastric emptying often stabilizes, and bowel habits may become more predictable again, though not everyone experiences full relief

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Limit sugary and processed foods : Foods high in sugar and processed ingredients can slow down weight loss