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This is an updated version of an article originally published November 2016.
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Indeed, adoption of the procedure in the US is low
However, peptides are inherently unstable in aqueous solutions, susceptible to hydrolysis, aggregation, oxidation, and deamidation, making formulation critical for stability
Sulfhydril groups present on plasma proteins can act as antioxidants by donating an electron to neutralize a free radical
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