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The intraperitoneal route was selected to ensure reliable dosing and consistent systemic exposure, as ROSU exhibits low oral bioavailability (approximately 20%) (Hanke et al

MarcatoPDeanCALiuR-ZCoyleKMBydounMWallaceMet al

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Expression of Akt1/2 , Irs1/2 and Insr , as well as several transcription factors important in adipocyte metabolism and function such as Pparg , Foxo1 , Cebpb and Tcf7l2 were reduced in adipose Ndufs2 KO mice

ALA possesses the unique ability to regenerate and recycle other depleted antioxidants back into their active states

ChemistrySelect 8 , e202300225 (2023)