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Metformin, the only drug in the biguanide drug class, manages blood sugar levels by reducing glucose production in the liver, decreasing glucose absorption in the intestines, and improving insulin sensitivity

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Females should aim for at least 2.7 liters (91 fl oz) daily, while males should aim for at least 3.7 liters (125 fl oz) daily

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10.1016/j.biopha.2022.113413 81 MohseniM.HosseinzadehP.CivitelliR.EisenS