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The vitamin is a cofactor for methionine synthase, which catalyzes the conversion of homocysteine to methioninerequired for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 substrates, including DNA, RNA, hormones, proteins, and lipids
Therapeutic potential of isorhamnetin following acetaminophen-induced hepatotoxicity through targeting NLRP3/NF-B/Nrf2
The mitochondrial pathway of apoptosis part II: the BCL-2 protein family
Because they do not cross the blood-brain barrier in significant systemic amounts, they lack the cardiovascular, hepatic, or gastrointestinal side effects common to systemic drugs
This is based on how well the patient responds and the severity of their deficiency
